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Urology

Urological Conditions

Benign Prostatic Hyperplasis (BPH)

Medications

A variety of medications are available to treatment the symptoms of BPH. Your doctor will assess the severity of your symptoms, and prescribe the most appropriate treatment.

Options for medication include:

Alpha blockers. Originally used to treat high blood pressure, these drugs relax the smooth muscle of the prostate and bladder neck, making it easier to urinate. They’re most often taken orally, once or twice a day just before bedtime, and work almost immediately. Side effects can include headaches, dizziness, light-headiness, low blood pressure, fatigue and difficulty breathing. Long-term risks and benefits have not been studied.

Below is a list of some commonly prescribed alpha blockers, including their generic name, brand name, and typical dosage:

  • Alfuzosin (UroXatral™), extended-release tablet taken once daily
  • Doxazosin (Cardura®), tablet taken once daily
  • Prazosin (Minipress®), capsule taken 2 or 3 times daily
  • Tamsulosin hydrochloride (Flowmax®), capsule taken once daily
  • Terazosin (Hytrin®), capsule taken once daily

5-Alpha-reductase inhibitors. While alpha blockers reduce the symptoms of BPH, these drugs can actually shrink the prostate. Studies suggest they work best for men with greatly enlarged prostates and can take a long time to work completely (though some improvement may be noticed after a few months). Commonly prescribed 5-Alpha reductase inhibitors are:

  • Finasteride (brand names Proscar®, Propecia®,)
  • Dutasteride (brand name Avodart™)

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