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Women's Health

Gynecology

The Timing of Menopause

Natural Menopause

While the average age for a woman in the United States to go through natural menopause is 51, a range of anywhere from 40 to 60 is still considered normal. There are a number of women who may experience natural menopause at a slightly earlier age than would be normal for them. They include:

  • Smokers (up to a year-and-a-half earlier than non-smokers)
  • Women who live at high altitudes
  • Women who have never been pregnant

“Instant” Menopause

Possibly as many as one in three women will go through “instant” menopause because of damage to the ovaries from surgery, radiation to the pelvic area or chemotherapy.
  • Removal of the ovaries. A bilateral oophorectomy means that both ovaries are removed. In this circumstance, your body immediately stops producing estrogen and progesterone. This can cause you to experience intense, even violent, symptoms and usually requires hormone replacement therapy to help you bridge the gap.

  • Hysterectomy and other pelvic surgeries. Surgeries without removal of the ovaries generally do not cause menopause. However, if the blood supply leading to your ovaries is damaged, they may deteriorate. In this case, symptoms, and the treatment you should consider, will depend on how fast you experience ovary failure.

  • Radiation. Pelvic radiation therapy is likely to cause permanent ovarian failure if the ovaries receive significant doses of radiation. If you receive low dose/short term treatment, your ovaries may recover. However, even if your periods resume, you may be infertile.

  • Chemotherapy. Depending on the drugs being used during chemotherapy, your menstrual periods may just become irregular or they may stop. Following chemotherapy, you may experience a few months up to several years of irregular ovarian function. Your periods may eventually come back (although you may remain infertile).

Premature ovarian failure

Menopause that takes place before the age of 40 and isn’t related to surgery, radiation, chemotherapy or other medications is called spontaneous premature menopause or premature ovarian failure (POD) and occurs in a very small percentage of women. It can occur as early as pre-puberty. When this happens to a young girl, she will not develop sexually nor will she start menstruation. In adults, the menstrual cycle will stop and the woman will be infertile. The reason for POF is unexplained in the majority of patients. Some suspected causes include:

  • Congenital abnormality–the ovaries are absent, underdeveloped or damaged at birth
  • Heredity/familial premature ovarian failure including chromosomal irregularities
  • Autoimmune disease–your body's immune system mistakenly attacks itself
  • Damage to the ovaries–this could be caused by trauma, hemorrhage from rupture of ovarian cysts or viral infections, such as the mumps