BPC-157: A muscle recovery supplement to consider

If you want to build muscle, lose fat, or boost your performance, recovery is essential for results. Over-training decreases your chances for a successful recovery as it increases your risk for injury. Effective recovery has a foundation in proper sleep and diet, but supplements can have a dramatic impact as well. One supplement, in particular, BPC-157, is making waves in the gyms and the medical community as reports of its healing process and recovery benefits spread.

What is BPC 157?

BPC-157 stands for Body Protection Compound, which reflects its healing process benefits that are getting so much attention. The “157” is a nod to the fact that the compound is a peptide chain built of 15 amino acids.

Amino acids are the byproduct of protein breakdown. They are also the building blocks of muscle and ligament tissue. When you drink a protein shake, for example, your body gets to work to break it down into these 20 usable amino acids.

While amino acids are natural, the particular sequence of BPC 157 is not, which is why you’ll often hear it referred to as a synthetic supplement. Don’t let this scare you off though as the benefits of this compound are incredible.

How BPC 157 is made

BPC 157 was first discovered in the gastric juices inside the human stomach that promote the breakdown of food, liquids, and supplements. In particular, one protein was isolated from these stomach acids in its unique 15-amino acid chain.

Available as both an oral and an injection-based supplement, BPC 157 via injection is far more popular and effective.

BPC 157 may help your body heal faster

The celebrated benefits of BPC 157 seem to come from the influence it has on a specific protein within the body called VEGFR2. Studies have shown that when BPC 157 is introduced, the presence of VEGFR2 increases in cells and the signaling pathway VEGFR2-Akt-eNOS is activated.

Why is this important? VEGFR2 and the signaling pathway directly promote blood flow, development of new blood vessels, and blood vessel repair during a process called angiogenesis. This is how BPC 157 works its healing properties throughout your body.


This strong piece of collagen-based tissue connects your muscles to your bones. The importance of tendons can’t be overstated as they make all exercises and movements possible. Tears and strains in tendons can keep you out of the gym several months. BPC has been shown to dramatically accelerate the repair and growth of injured tendon tissue. As a preventative measure, BPC 157 might help you avoid serious tendon-related injuries.

Ligaments are found in your joints such as elbows and ankles. This tissue bonds together cartilage and muscle, or two different bones. Just as important as tendons, ligaments are a strong link in your body chain. Oral supplementation of BPC 157 has been shown to improve the ligament healing rate of injured ligaments. Again, taking it during periods of extreme exercise can be an effective way to prevent serious injury.


When you step into the gym, dive into a pool and run on a track, muscle tissue promotes these types of performance. It also helps with weight loss and looks great when developed. Incredibly resilient, muscle tissue isn’t invincible and it’s pushed past its limits all too often in exercise and sports.

BPC 157 is a proven way to promote muscle healing whether you’re sore or you’ve been injured. Studies show that BPC 157 was able to restore movement and trigger faster healing of a crushed calf muscle. The BPC 157 was injected near the site of the injury, which may explain how well it worked.

In another study, BPC 157 was shown to promote the release of growth hormone, a necessary component for muscle and tendon healing.


The absorption of the nutrients that you eat each day takes place in the intestines. This is also the site for certain diseases and damage done by over-the-counter medications.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are readily available in high doses at your local market or pharmacy. Despite warnings of ulcers and stomach bleeding, people continue to take NSAIDs for muscle pain. Over time, these drugs can do severe damage to your stomach and intestines. BPC 157 has been shown to reverse this damage, helping to stop bleeding and restore the health of your stomach.

Doctors have seen an increase in the number of patients with inflammatory bowel disease (IBD) over the last two decades. This is a term used to describe several conditions related to the digestive tract, gastric, and intestines. Symptoms could include ulcers, bleeding, pain, and inflammation. Studies show that BPC 157 is an effective way to alleviate the symptoms of IBD and treat the disease.


A common but preventable disease, periodontitis is the inflammation and swelling of your gums. It can eventually lead to tooth loss. The anti-inflammatory properties of BPC 157 helped to alleviate the swelling attributed to the disease. What’s more, researchers suggest that the healing benefits of BPC 157 could be an effective way to treat periodontitis.


Powerlifter or football players, the risk for fracture and breaks of bones is always present for those involved in fitness. Damage to bones can bench a player for a season or keep the average person out of the gym for up to a year.

BPC 157 has shown immense potential as a way to encourage the healing and development of bone tissue. It’s been shown to be effective as a complement to bone marrow application, helping to dramatically heal fractures in 2 weeks. BPC 157 has also been shown to heal and restore proper function in tendon-to-bone sites.

Does BPC 157 really work?

BPC 157 has been the subject of multiple studies, but despite its popularity in scientific literature, the question remains: Is BPC 157 an effective supplement for human consumption?

A History of BPC 157 clinical trials

Studies on BPC 157 began in full swing in the 1970s with a focus on isolating the compound and applying it to stomach-based issues. Eventually, the healing potential of BPC 157 was extended to other parts of the body, most notably the tendons and muscle tissue.

To date, there are no known scientific publications with humans as the subject of BPC 157 studies. All studies have been done using animal test subjects. One human-based study was completed in late 2016, but the results of the study have yet to be released. What’s more, the sponsor of the study recalled the results before they were placed through quality control. With that said, it’s unlikely we’ll see what happened in this study.

In the studies that are available, all BPC 157 compounds were tested on rats. Injection sites usually varied based on the site of injury as rats often underwent intentional toxic or surgical damage. Time after time, the rats provided with BPC 157 showed a marked improvement in healing and development. The damaged sites of control rats (those who did not receive BPC 157) showed no improvement.

Here are some other noteworthy studies:

Wound Healing

BPC 157 was shown to speed up wound healing from burn-related injuries.

Brain-Gut Connection

The scientific community is finally revealing the connection that our guts have on the rest of the body, particularly the brain. One study showed that BPC 157 was able to strengthen the brain-gut connection; thereby improving immune reactions to foreign bodily invaders.

Brain Injury

Continuing with the idea that BPC 157 is good for your brain, one study on animal test subjects took rats and subjected them to an intentional traumatic brain injury via a falling weight. The rats that were injected with BPC 157 showed less damage including a lower level of lesions and hemorrhaging.

Is BPC 157 safe to use?

Although it has not been tested on humans, all of the studies mentioned above confirmed that BPC 157 was completely safe to use. Reviews across the internet show similar findings as users report healing benefits and no toxic drawbacks.

BPC 157 side effects

As mentioned above, in animal studies there have been no reported negative side effects. In user-submitted reviews, no person has reported any side effects related to BPC 157.

How to buy BPC 157

After reading that long list of proven benefits, your first thought is going to be how you can buy BPC 157. It is not available in commercial stores or over-the-counter pharmacies. You can find it online through a number of different providers; however, these supplement stores probably are not regulated.

Do you need a prescription?

Since BPC 157 is not considered an active medication, no prescription is needed to buy it. As mentioned above, most buy it through online stores. Be sure to do your research into the website before you buy BPC 157 from them.

BPC 157: Oral vs. injection

BPC 157 is available in both an oral supplement and injection-based form. The oral-based supplement of BPC 157 is historically unreliable as the supplement is rarely fully assimilated into the body. Most of the benefits occur within the stomach and digestive tract, and little to no results are observed in muscles, tendons, and ligaments.

In order to experience the highest level of benefit from BPC 157 in these areas, you’ll want to use an injection-based method. You can purchase BPC 157 along with a set of simple injection needles. Nearly all of the studies mentioned above-used injections on the rats, and when you read through user reviews, the best results were from injecting BPC 157 near the site of concern (e.g., injecting in the hip to improve hip flexion).

The recommended BPC 157 dosage

Since BPC 157 is not an active medication, and there have been no human-based trials performed, a set dosage is not explicitly defined. With that said, based on the studies above and supplement company recommendations, an unofficial guide to dosages is as follows:

  • 100-pound person: 75 micrograms (μg)
  • 150 lb. person: 110 μg
  • 200 lb. person: 145 μg
  • 250 lb. person: 180 μg
  • 300 lb. person: 215 μg

There are reports of users supplementing with up to 700 μg per day, split between two or three doses. However, if you’ve never used BPC 157 before, it would be best to start at the recommended dosage above, test your tolerance, and slowly increase your dosage by 5 μg.

BPC 157 review

Given that the supplement industry is full of false promises, it’s easy to look at BPC 157 and raise an eyebrow. There are no human studies, and despite being researched for almost 50 years, it’s still absent in the medical world as a reasonable treatment for injuries and disease.

With that said, it’s hard to ignore the science that has come out on BPC 157. Although the studies have been conducted on rats, it’s important to remember that all compounds are tested on rats before human testing. What’s more, the results that have come out from these animal-based studies have been extremely promising at their worst.

The healing benefits reported in studies seem to have merit as more and more people are getting their hands on BPC 157 and echoing the same. YouTube video reviews and blogs all reflect the idea that injection-based BPC 157 is a safe and effective way to promote site-specific healing of muscle, tendons, and ligaments.

Is BPC 157 a miracle cure? No, but is it a proven way to promote rapid recovery. It seems so.

The last word on BPC 157

If there was ever a supplement to hit the market that pulled its own weight (outside of the classics), BPC 157 is it. With nearly 50 years of positive results in clinical trials and no side effects in animal testing, BPC 157 is a recovery and healing-focused supplement that you can count on. The only downside to BPC 157 is that it’s best used via injection, making it a chore for the needle-weary.